Qiaoqiao Ci

Protein expression and purification.

My research is committed to producing large quantities of the target protein, purifying it to remove contaminants, and verifying its efficacy and safety. It is crucial in vaccine development as it ensures the production of high-quality, functional proteins that serve as antigens of the vaccine.

Nanovaccines against infectious diseases.

My goal is to develop a hybrid nanoparticle-based broadly effective vaccine for porcine epidemic diarrhea virus using purified proteins as antigens.

Ci, Qiaoqiao, Yawen He, and Juhong Chen. "Novel Anti-CRISPR-Assisted CRISPR Biosensor for Exclusive Detection of Single-Stranded DNA (ssDNA)." ACS sensors 2024:1162-1167.

Kasputis, Tom, Yawen He, Qiaoqiao Ci, and Juhong Chen. "On-Site Fluorescent Detection of Sepsis-Inducing Bacteria using a Graphene-Oxide CRISPR-Cas12a (GO-CRISPR) System." Analytical Chemistry 2024:2676-2683.

 Zhao, Xue, Yawen He, Shengjie Shao, Qiaoqiao Ci, Lin Chen, Xiaonan Lu, Qian Liu, and Juhong Chen. "CRISPR/Cas14 and G-Quadruplex DNAzyme-Driven Biosensor for Paper-Based Colorimetric Detection of African Swine Fever Virus." ACS sensors 2024:2413-2420.

Qiaoqiao Ci, Yuanyuan Wang, Ben Wu, Emerson Coy, Jiao jiao Li, Daoyong Jiang, Pengfei Zhang, * and Guocheng Wang*. Fe-Doped Carbon Dots as NIR-II Fluorescence Probe for In Vivo Gastric Imaging and pH Detection. Advanced Science, 2023, 220627.

Qiaoqiao Ci, Hong Yang, Yuanzhi Bian, Zheng Li, Jinhua Liu*, JiFu Wei, Naidi Yang, Juhong Chen, Lin Li* and Chengwu Zhang*. An in situ fluorescent copolymer dots-based kit for the specific detection of monoamine oxidase-A in cell/tissue/human prostate cancer. Sens. Actuators B Chem, 2023, 134655.

Qiaoqiao Ci, Xiaofei Qin, Jinhua Liu, Zheng Li, Haidong Yu, Cheng-Wu Zhang*, Lin Li* and Wei Huang. Mitochondria-Targeted Polydopamine Nanoprobes for Visualizing Endogenous Sulfur Dioxide Derivatives in Rat Epilepsy Model. Chemical Communication, 2020, 56:11823-11826.

Qiaoqiao Ci, Jinhua Liu, Xiaofei Qin, Linqi Han, Hai Li, Haidong Yu, Kah-Leong Lim, Cheng-Wu Zhang*, Lin Li* and Wei Huang. Polydopamine Dots-Based Fluorescent Nanoswitch Assay for Reversible Recognition of Glutamic Acid and Al3+ in Fluid Samples and Living Cell. ACS Applied Materials & Interfaces, 2018, 10: 5760-5769.

Linqi Han, Riri Shi, Chenqi Xin, Qiaoqiao Ci, Jingyan Ge, Jinhua Liu, Qiong Wu, Cheng-wu Zhang*, Lin Li* and Wei Huang. Mitochondrial Specific H2Sn Fluorogenic Probe for Live Cell Imaging by Rational Utilization of a Dual-Functional-Photocage Group. ACS Sensors, 2018, 3: 1622-1626.